Review



anti suv3  (Proteintech)


Bioz Verified Symbol Proteintech is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    Proteintech anti suv3
    Anti Suv3, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUPV3L1+Antibody/bio_rxiv__64898__2026__01__06__698045-223-77-78
    Average 94 stars, based on 3 article reviews
    anti suv3 - by Bioz Stars, 2026-09
    94/100 stars

    Images

    Related Articles

    other:

    Article Title: Mitochondrial dsRNA: A Hidden Source of Immunogenic RNA in ADAR1 Deficiency
    Article Snippet: Antibodies used in this study are as listed: anti-ADAR1 (CST, #14175; for detecting human ADAR1), anti-ADAR1 15.8.6 (Santa Cruz, sc-73408; for detecting mouse ADAR1), anti-β actin HRP (Santa Cruz Biotechnology, sc-47778HRP), anti-mouse IgG HRP-linked (Cell Signaling Technology, 7076), anti-rabbit IgG HRP-linked (Cell Signaling Technology, 7074), anti-GFP (Santa Cruz, SC-9996), anti-MDA5 (Cell Signaling Technology, 5321), anti-TBK1 (Cell Signaling Technology, 3504), anti-MAVS (Cell Signaling Technology, 3993), anti-IRF3 (Cell Signaling Technology, 11904), anti-NFκB (Cell Signaling Technology, 8242T), anti-TOM20 (ProteinTech, 11802-1-AP), anti-SUV3 (ProteinTech, 12826-1-AP), anti-PNPT1 (ProteinTech, 14487-1-AP), anti-HSP60 (ProteinTech, 66041-1-Ig), anti-MIA40 (ProteinTech, 21090-1-AP), anti-SOD2 (ProteinTech, 66474-1-Ig), anti-GRSF1 (abcam, ab205531), anti-REXO2 (Abcam, ab206694), anti-Alpha-Tubulin (Santa Cruz, sc-32293), anti-Fibrillarin (Abcam, ab4566).



    Similar Products

    suv3  (Bethyl)
    93
    Bethyl suv3
    Suv3, supplied by Bethyl, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUV3+Antibody/pm41800619-461-24-25
    Average 93 stars, based on 1 article reviews
    suv3 - by Bioz Stars, 2026-09
    93/100 stars
    		  Buy from Supplier
    anti suv3  (Proteintech)
    94
    Proteintech anti suv3
    Anti Suv3, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUPV3L1+Antibody/bio_rxiv__64898__2026__01__06__698045-223-77-78
    Average 94 stars, based on 1 article reviews
    anti suv3 - by Bioz Stars, 2026-09
    94/100 stars
    		  Buy from Supplier
    rabbit α suv3  (Bethyl)
    93
    Bethyl rabbit α suv3
    (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, <t>SUV3,</t> and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.
    Rabbit α Suv3, supplied by Bethyl, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUV3+Antibody/bio_rxiv__2025__08__04__668575-291-24-26
    Average 93 stars, based on 1 article reviews
    rabbit α suv3 - by Bioz Stars, 2026-09
    93/100 stars
    		  Buy from Supplier
    santa cruz suv3 supv3l1  (Santa Cruz Biotechnology)
    92
    Santa Cruz Biotechnology santa cruz suv3 supv3l1
    (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, <t>SUV3,</t> and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.
    Santa Cruz Suv3 Supv3l1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUV3+Antibody/pm39209534-327-54-54
    Average 92 stars, based on 1 article reviews
    santa cruz suv3 supv3l1 - by Bioz Stars, 2026-09
    92/100 stars
    		  Buy from Supplier
    santa cruz dna if  (Santa Cruz Biotechnology)
    92
    Santa Cruz Biotechnology santa cruz dna if
    (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, <t>SUV3,</t> and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.
    Santa Cruz Dna If, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUV3+Antibody/pm39209534-327-29-29
    Average 92 stars, based on 1 article reviews
    santa cruz dna if - by Bioz Stars, 2026-09
    92/100 stars
    		  Buy from Supplier
    abcam suv3 supv3l1 wb  (Santa Cruz Biotechnology)
    92
    Santa Cruz Biotechnology abcam suv3 supv3l1 wb
    (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, <t>SUV3,</t> and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.
    Abcam Suv3 Supv3l1 Wb, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUV3+Antibody/pm39209534-327-24-29
    Average 92 stars, based on 1 article reviews
    abcam suv3 supv3l1 wb - by Bioz Stars, 2026-09
    92/100 stars
    		  Buy from Supplier
    abcam suv3 supv3l1 wb  (Proteintech)
    94
    Proteintech abcam suv3 supv3l1 wb
    (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, <t>SUV3,</t> and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.
    Abcam Suv3 Supv3l1 Wb, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUPV3L1+Antibody/pm39209534-327-24-49
    Average 94 stars, based on 1 article reviews
    abcam suv3 supv3l1 wb - by Bioz Stars, 2026-09
    94/100 stars
    		  Buy from Supplier
    proteintech pnpase wb  (Santa Cruz Biotechnology)
    92
    Santa Cruz Biotechnology proteintech pnpase wb
    (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, <t>SUV3,</t> and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.
    Proteintech Pnpase Wb, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUV3+Antibody/pm39209534-327-49-54
    Average 92 stars, based on 1 article reviews
    proteintech pnpase wb - by Bioz Stars, 2026-09
    92/100 stars
    		  Buy from Supplier
    anti suv3  (Santa Cruz Biotechnology)
    92
    Santa Cruz Biotechnology anti suv3
    (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, <t>SUV3,</t> and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.
    Anti Suv3, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUV3+Antibody/pmc08601606-255-55-56
    Average 92 stars, based on 1 article reviews
    anti suv3 - by Bioz Stars, 2026-09
    92/100 stars
    		  Buy from Supplier
    rabbit anti suv3  (Bethyl)
    93
    Bethyl rabbit anti suv3
    (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, <t>SUV3,</t> and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.
    Rabbit Anti Suv3, supplied by Bethyl, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+suv3/SUV3+Antibody/pmc06570621-456-28-31
    Average 93 stars, based on 1 article reviews
    rabbit anti suv3 - by Bioz Stars, 2026-09
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, SUV3, and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.

    Journal: bioRxiv

    Article Title: RNA triggers chronic stress during neuronal aging

    doi: 10.1101/2025.08.04.668575

    Figure Lengend Snippet: (A) Screen captures from the Agilent TapeStation Analysis Software v4.1.1 of RNA ScreenTapes loaded with samples from throughout the dsRNA purification protocol in HEK293T cells. Exogenous (exo.) dsRNA of a known size (∼150 bp) was tracked throughout the purification. (B) Volcano plot of the log 2 (Fold Change) of all MT-RNA transcripts identified by dsRNA-Seq in the input and immunoprecipitation (IP) samples of the Tdiff.2 transdifferentiated neuron line. (C) Same as (B) but for Tdiff.5 transdifferentiated neurons. (D) Same as (B) but for iPSC-diff.1 neurons. (E) Volcano plot of RNA-seq in transdifferentiated neurons (Tdiff.1/2/4/5) versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). Orange data points denote nuclear-encoded mitochondrial genes whereas yellow data points denote MT-RNA transcripts. The MT-ND6, SUV3, and PNPT1 transcripts are indicated on the plot. (F) Boxplot of the Log 2 (Fold Change) of all transcripts (gray), nuclear-encoded mitochondrial transcripts (orange), and MT-RNA transcripts (yellow) in transdifferentiated neurons versus iPSC-derived neurons (n=3 replicates per line; N=4 lines per cohort). (G) Visualization of representative mitochondrial sequencing reads detected by dsRNA-Seq and PKR CLIP in the Tdiff.1 transdifferentiated neuron line. The shaded region denotes the reverse-transcribed MT-ND6 gene. The range of the y-axis values is denoted on the right side of the genomic track and was fixed for each pair of input and IP samples.

    Article Snippet: The following antibodies were used for eCLIP: 1 μg Rabbit α-PKR (Cell Signaling Technology #12297S); 10 μg Rabbit α-PNPT1 (Bethyl #A303-917A); and 2 μg Rabbit α-SUV3 (Bethyl #A303-056A).

    Techniques: Software, Purification, Immunoprecipitation, RNA Sequencing, Derivative Assay, Sequencing, Reverse Transcription

    (A) Additional airyscan immunofluorescence-FISH images of the mitochondrial marker TOM70 (magenta) and MT-ND6 transcript (green) in Tdiff.1 neurons. Green arrowheads denote cytoplasmic MT-ND6 puncta; the white arrows denote the intensity profiles in the adjacent plot. Yellow Scale Bar = 2 μm. (B) Same as (A) but for the MT-RNR1 transcript in various transdifferentiated neuron lines (Tdiff.1/2/4). (C) Airyscan immunofluorescence images of the indicated mitochondrial proteins in Tdiff.1 neurons. Yellow Scale Bar = 2 μm. (D) Visualization of representative mitochondrial sequencing reads detected by PNPT1 eCLIP (n=2 replicates) in the indicated neuronal lines. The shaded region denotes the reverse-transcribed MT-ND6 gene. (E) Same as (D) but for SUV3 eCLIP.

    Journal: bioRxiv

    Article Title: RNA triggers chronic stress during neuronal aging

    doi: 10.1101/2025.08.04.668575

    Figure Lengend Snippet: (A) Additional airyscan immunofluorescence-FISH images of the mitochondrial marker TOM70 (magenta) and MT-ND6 transcript (green) in Tdiff.1 neurons. Green arrowheads denote cytoplasmic MT-ND6 puncta; the white arrows denote the intensity profiles in the adjacent plot. Yellow Scale Bar = 2 μm. (B) Same as (A) but for the MT-RNR1 transcript in various transdifferentiated neuron lines (Tdiff.1/2/4). (C) Airyscan immunofluorescence images of the indicated mitochondrial proteins in Tdiff.1 neurons. Yellow Scale Bar = 2 μm. (D) Visualization of representative mitochondrial sequencing reads detected by PNPT1 eCLIP (n=2 replicates) in the indicated neuronal lines. The shaded region denotes the reverse-transcribed MT-ND6 gene. (E) Same as (D) but for SUV3 eCLIP.

    Article Snippet: The following antibodies were used for eCLIP: 1 μg Rabbit α-PKR (Cell Signaling Technology #12297S); 10 μg Rabbit α-PNPT1 (Bethyl #A303-917A); and 2 μg Rabbit α-SUV3 (Bethyl #A303-056A).

    Techniques: Immunofluorescence, Marker, Sequencing, Reverse Transcription